论文羟苯磺酸钙致血肌酐结果假性偏低临床观察是大学硕士与本科羟苯磺酸钙毕业论文开题报告范文和相关优秀学术职称论文参考文献资料下载，关于免费教你怎么写羟苯磺酸钙方面论文范文。
[摘 要] 目的 观察慢性肾脏病（CKD）3～5期患者服用羟苯磺酸钙后采用肌氨酸氧化酶法检测血肌酐结果偏差水平,探讨羟苯磺酸钙对肌氨酸氧化酶法检测血肌酐的影响程度. 方法 选取82例CKD3～5期未行透析治疗的患者,随机分为两组,对照组给予常规治疗,实验组在常规治疗基础上加用羟苯磺酸钙0.5 g,3次/d口服,分别检测两组治疗前、治疗后1周血肌酐水平,实验组加测停用羟苯磺酸钙1周后血肌酐水平,对照组亦检测同期血肌酐水平. 结果 两组患者治疗1周后血肌酐水平較治疗前均有下降,实验组血清肌酐最低下降47.3 μmol/L,最高下降295.5 μmol/L,下降程度明显高于对照组,差异具有统计学意义（P<0.01）；实验组停用羟苯磺酸钙1周后血肌酐值较羟苯磺酸钙治疗1周后血肌酐值明显上升,与对照组同期血肌酐值相比较,差异无统计学意义（P>0.05）.结论 羟苯磺酸钙对肌氨酸氧化酶法检测 CKD 3～5期患者血肌酐结果有明确干扰作用,检测值在一定程度上低于实际水平,建议避免在评估肾功能期间服用羟苯磺酸钙.
[关键词] 羟苯磺酸钙；血肌酐；肌氨酸氧化酶法；慢性肾脏病（CKD）；假性偏低
[中图分类号] R961；R446.11 [文献标识码] B [文章编号] 1673-9701（2018）05-0079-03
[Abstract] Objective To observe the deviation level of serum creatinine detected by sarcosine oxidase in patients with stage 3-5 chronic kidney disease（CKD） after taking calcium dobesilate, and to explore the effect degree of calcium dobesilate on the method of sarcosine oxidase in detecting serum creatinine. Methods A total of 82 patients with CKD stage 3-5 without dialysis were randomly divided into two groups. The control group was given routine treatment. The experimental group was given 0.5 g calcium dobesilate orally, 3 times/day, on the basis of routine treatment. The levels of serum creatinine in both groups were measured before treatment and one week after treatment. The level of serum creatinine in the experimental group after stopping the calcium dobesilate for one week was also measured. And the serum creatinine level in the control group in the same period was detected. Results Serum creatinine decreased after 1 week of treatment in both groups. The serum creatinine in experimental group decreased 47.3 μmol/L in the lowest and decreased 295.5 μmol/L in the highest, and the degree of decline in the experimental group was significantly higher than that of control group, with significant difference（P<0.01）. In the experimental group, the serum creatinine value after stopping calcium dobesilate for one week was significantly higher than that after treatment of calcium dobesilate for one week, which has no significant difference compared with that of the control group（P>0.05）. Conclusion Calcium dobesilate has clear interference effect on the method of sarcosine oxidase in detecting serum creatinine in CKD stage 3-5 patients. The test value is lower than the actual level to a certain degree. It is recommended to oid taking calcium dobesilate during assesent of renal function.
[Key words] Calcium dobesilate； Serum creatinine； Sarcosine oxidase； Chronic kidney disease （CKD）； Pseudo-low
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参考文献：
1、 血清肌酸激酶测定在预测急性一氧化碳中毒预后的临床 【摘要】 目的 觀察血清肌酸激酶（CK）在预测急性一氧化碳中毒（ACOP）预后的应用价值。方法 48例ACOP患者， 按照中毒程度不同分为轻度。
2、 羟苯磺酸钙治疗糖尿病肾病安全性临床效果 DOI：10 16658 j cnki 1672-4062 2016 18 020[摘要] 目的 探讨羟苯磺酸钙治疗糖尿病肾病的临床效果及安全。
3、 疏血通注射液治疗糖尿病周围神经病变临床疗效观察 [摘要] 目的 观察疏血通注射液治疗糖尿病周围神经病变的临床疗效。方法 于2014年4月—2016年11月选取该院收治的100例患者随机分为实验。
4、 硝苯地平联合厄贝沙坦治疗糖尿病合并高血压疗效观察 [摘要] 目的 对糖尿病合并高血压患者联合应用硝苯地平与厄贝沙坦进行治疗的临床效果展开观察与分析。方法 将98例于2015年8月—2017年6月。
5、 十二烷基苯磺酸钠生产技术培训 十二烷基苯磺酸钠的应用及发展：随着精细化工及各种化工产品生产的蓬勃发展，各种化工产品的市场需求量不断增大，生产精细化工及各种化工产品的相关原料备。
6、 十二烷基苯磺酸钠个人办厂赚钱快 十二烷基苯磺酸钠，产品具备渗透性、润湿性、乳化性、分散性、速溶性、界面性、亲水亲油及发泡与消泡的多种功能，广泛用于民用及工业用洗涤剂、纺织工业清。